🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Contact Aspiration Versus Stent Retriever for Recanalisation of Acute Stroke Patients With Basilar Artery Occlusion: The Posterior Circulation ASTER Randomized Trial Protocol

RecruitingNAAges 18 Years - anyAllHopital Foch
NCT05320263 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Acute ischemic stroke (AIS) patients with basilar artery occlusion (BAO) present a devastating, life-threatening prognosis. Urgent recanalization with endovascular mechanical thrombectomy is routinely performed in patients with BAO although the level of evidence is lower than that in anterior circulation occlusions (randomization in this population versus medical treatment alone having been impossible in recent studies). Recently, a large retrospective study supports the interest of thrombectomy in this population . Speed and grade of the recanalisation have a major impact on clinical outcome. Favorable outcome at 90 days is strongly associated with the successful recanalization status at the end of the endovascular procedure (OR=4.57, 95%CI=1.24-16.87, P=0.023). First pass effect has been shown to be a strong marker of efficacy of endovascular procedure with significant correlation w

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: Age ≥ 18 years * AIS with BAO on non-invasive imaging (CT or MRI) * Eligible for thrombectomy : groin puncture undergone within 24 hours of first symptoms or of last time the patient was seen normal * Being covered by a national health insurance * Informed consent obtained from the patients/his proxy or following an emergency procedure Exclusion Criteria: * Known or suspected pre-existing (chronic) large vessel stenosis / occlusion in the symptomatic territory (basilar artery) * Severe contrast medium allergy or absolute contraindication to use of iodinated products * Clinical history, past imaging or clinical judgment suggesting intracranial stenosis of the basilar artery * Pregnancy (urine or serum beta HCG test for women of child-bearing potential) * Person deprived of liberty * Patient benefiting from a legal protection (guardianship or curatorship)
💊

What it tests

  • Contact aspiration Thrombectomy
  • Stent retriever thrombectomy
📍

Where

12 sites
Chu Bordeaux
Bordeaux, France
CHU Caen
Caen, France
CHU Limoges
Limoges, France
CHU Montpellier
Montpellier, France
Chru Nancy
Nancy, France
Chu Nantes
Nantes, France
APHP - Pitié Salpêtrière
Paris, France
Fondation Adolphe de Rothschild
Paris, France

…and 4 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy