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Crural Repair During Laparoscopic Sleeve Gastrectomy in Patients With a Lax Gastroesophageal Junction

RecruitingNAAges 21 Years - 65 YearsAllSengkang General Hospital
NCT05330910 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background: Laparoscopic sleeve gastrectomy (LSG) is one of the commonest bariatric procedures. However, it is associated with postoperative gastroesophageal reflux disease (GERD) and erosive esophagitis (EE). The investigators' preliminary study suggests that the incidence of postoperative GERD and EE appears to be correlated with the preoperative presence of a lax gastroesophageal flap valve and hiatal hernia. Hypothesis/ Aim: To investigate the impact of a concomitant hiatal hernia repair with LSG on the incidence of postoperative EE. Significance: For patients with pre-existing EE, most surgeons will recommend a laparoscopic Roux-en-Y gastric bypass (LRYGB) as their primary bariatric procedure. However, compared to LSG, LRYGB is a technically more demanding procedure with increased morbidity and long term nutritional deficiencies. For asymptomatic patients at risk of postoperati

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📋 Eligibility rules (as published)
Inclusion Criteria: * 21-65 years old * Able to provide informed consent * Hill's grade III gastroesophageal junction on preoperative endoscopy * Opted to undergo laparoscopic sleeve gastrectomy as their bariatric procedure Exclusion Criteria: * Unable or unwilling to provide informed consent * Contraindications to laparoscopic sleeve gastrectomy * Opted not to undergo laparoscopic sleeve gastrectomy * Had previous upper gastrointestinal surgery * Had documented erosive esophagitis on preoperative endoscopy * Had Hill's grade I, II or IV gastroesophageal junction on preoperative endoscopy
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What it tests

  • Laparoscopic sleeve gastrectomy with concomitant hiatal hernia repair arm
  • Laparoscopic sleeve gastrectomy arm
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Where

2 sites
Singapore General Hospital
Singapore, Singapore
Sengkang General Hospital
Singapore, Singapore
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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