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Impact of Propofol-Based Total Intravenous Anesthesia Versus Anesthesia With Sevoflurane on Long-term Outcomes With Patients Undergoing Elective Excision of Primary Liver Tumors

RecruitingPhase 4Ages 20 Years - 80 YearsAllKaohsiung Medical University Chung-Ho Memorial Ho…
NCT05331911 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary Hepatocellular carcinoma. The study will enroll approximately 500 volunteers to compare the progression-free or overall survival in patients undergoing elective partial hepatectomy for primary liver tumors between propofol and sevoflurane for the maintenance of anesthesia.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Twenty to eighty-year-old. 2. ASA class I-III. 3. Patients undergoing partial hepatectomy for hepatocellular carcinoma under general anesthesia. Exclusion Criteria: 1. Severe mental disorder 2. Pregnant or lactating women 3. Morbidly obese 4. Allergy to any of the drugs used in this study 5. Recurrent tumor or repeat surgery 6. Biopsy cases 7. Incomplete data collection before the surgery 8. Palliative treatment after surgery 9. simultaneous treatment of other malignancies 10. Combined propofol and inhalation anesthesia or other anesthetics, such as ketamine or dexmedetomidine 11. Diagnosed as benign liver tumor 12. Emergency surgery
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What it tests

  • Propofol
  • Sevoflurane
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Where

1 site
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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