China HeadAche DIsorders RegiStry

Inclusion Criteria: 1. Age ≥ 12 years old,Any gender; 2. The first onset age of primary headache was less than 50 years old(Age \<65 years at first diagnosis of chronic migraine); 3. patients with primary headache (migraine, tension headache and other types of primary headache) or primary headache complicated with MOH according to ICHD-3; 4. Sign the informed consent form. Exclusion Criteria: 1. According to the ICHD-3 diagnostic criteria, there are still headaches directly related to secondary factors (except drug overuse) at the time of enrollment; 2. Those who cannot be diagnosed as primary headache or primary headache combined with medication overuse headache according to ICHD-3; 3. According to DSM-V diagnostic criteria, patients with severe mental diseases (such as schizophrenia, mental disorders associated with mental retardation, etc.); 4. Patients with severe organic diseases, such as malignant tumors, and the expected survival time is less than 1 year; 5. Pregnant,planning pregnancy or Lactating women; 6. Subjects participating in other clinical trials; 7. Unable to cooperate to complete the follow-up due to geographical or other reasons