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โ† Trials
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Oxalate and Citrate

RecruitingNAAges 18 Years - 70 YearsAllUniversity of Chicago
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In plain words

What the trial is, and whether it could suit you

This is a single-center study that aims to earn more about how two different compounds found in food, oxalate and citrate, may affect a person's chances of forming kidney stones.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: Stone formers: * Age 18-70 * History of at least one calcium-based kidney stone Non-stone formers (controls): * Age 18-70 * No history of kidney stone * 24-hour urine oxalate within lab normal (\<50mg/day) Exclusion Criteria: * History of primarily uric acid, cysteine, or struvite stones. * History of severe acid-base abnormality, very low (less than 100mg/day) or very high (greater than 1500mg/day) urine citrate. * Any controls or stone-forming participants who cannot stop diuretic medication or alkali supplementation for the course of the study period. * Non-stone formers and stone-formers with extreme levels of urine citrate will be excluded from this small initial study to reduce heterogeneity and remove focus from the extremes of citrate levels.
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What it tests

  • Kidney stones Normal controls Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic
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Where

1 site
University of Chicago Medical Center
Chicago, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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