Home Based Personalized Training and Video Consultation in Mitochondrial Myopathies: Study of Efficacy and Tolerance.

Inclusion criteria: * patient over 18 years-old, * with genetically-confirmed mitochondria myopathy, * with mitochondrial DNA mutation, * clinically dominant myopathic-like disorders according investigator, * able to walk with or without assistance, * likely to be followed for at least one year without interruption by video consultation (implying internet connexion with computer and camera or smartophone), * having given the written and informed consent and being social security member. * For patients in childbearing age, she must have used at least one month if reliable contraception. Exclusion criteria: * patient wih pathology or comorbidity incompatible with the conduct of the study according the investigator during inclusion visit, * patient with physical condition incompatible with training program according investigator during inclusion visit, * patient having a physical tiredness and/or myalgia during last week with an intensity of 6 on visual and analog scale, * pregnant or nursing patient, * patient expecting pregnancy during the course of the study, * patient protected by law or under guardianship or curatorship, or not able to participate in a clinical trial under L.1121-16 article of French Public Health Regulations.