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Effects and Safety of Diabetic GUideline Algorithm Implementation Performed by Primary Care Physicians in the Community

RecruitingNAAges 65 Years - anyAllShanghai Zhongshan Hospital
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In plain words

What the trial is, and whether it could suit you

The Effects and Safety of Diabetic GUideline Algorithm Implementation in the Community (GUARD-Community) study is a 2-arm, cluster-randomized control trial to evaluate the effect and safety of guideline algorithm intervention performed by primary care physicians on cardiovascular and renal outcomes in elderly patients with high risk in community.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * ①Males or females aged 65 and above (≥65) receive treatment from the local community health service center; * ②Diagnosed type 2 diabetes (ADA criteria): * A. Typical symptoms of diabetes + random blood sugar ≥ 11.1mmol/L; * B. Fasting blood glucose (FPG) ≥ 7.0mmol/L (fasting blood glucose is defined as no caloric intake within 8 hours); * C. Oral glucose tolerance test 2h blood glucose (OGTT) ≥ 11.1mmol/L (2h after meal); * D. have been treated with antidiabetic drugs; * Each blood sugar test must be repeated to confirm the diagnosis; * ③Complicated with chronic kidney disease and/or very high/high risk of cardiovascular disease, meet any one of the following: * A. ASCVD, including coronary heart disease, cerebral infarction, peripheral vascular disease; * B. Or target organ damage (albuminuria, renal impairment with eGFR ≥ 30 ml/min/1.73m2, left ventricular hypertrophy or retinopathy); * C. ≥ 3 major risk factors (age ≥ 65 years old, hypertension, dyslipidemia, smoking, obesity ); * D. Diabetes duration ≥ 10 years, with any one traditional cardiovascular risk factor such as advanced age, obesity, smoking, sedentary, family history of cardiovascular disease, hypertension, abnormal lipid metabolism. Exclusion Criteria: * ①Pregnant women or women planning to become pregnant; * ②eGFR\<30 mL/min/1.73m2 (CKD-EPI formula); * ③Patient cannot be followed up for 36 months (due to health condition or migration); * ④Unwilling or unable to sign the informed consent; * ⑤Type 1 diabetes;
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What it tests

  • Intensive guideline algorithm implementation
  • Conventional guideline algorithm implementation
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Where

13 sites
Xiangcheng Second People's Hospital
Suzhou, China
Caohu Community Healthcare Center
Suzhou, China
Huangqiao Community Healthcare Center
Suzhou, China
Xiangcheng People's Hospital.
Suzhou, China
Yuanhe Community Healthcare Center
Suzhou, China
Xiangcheng Third People's Hospital
Suzhou, China
Taiping Community Healthcare Center
Suzhou, China
Yangchenghu People's Hospital
Suzhou, China

…and 5 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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