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Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

RecruitingPhase 3Ages 18 Years - anyAllUniversity of Texas Southwestern Medical Center
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Adult patients (age โ‰ฅ18 years old) 2. Having endoscopic procedure at CUH with anesthesia 3. ASA 3 or above 4. Ejection Fraction test result available Exclusion Criteria: 1. Known allergies or adverse reactions to study drugs or study drug components or preservatives 2. Patient refusal 3. Clinician refusal 4. Documented cognitive impairments precluding subject ability to consent for themselves unless a surrogate documented legally acceptable decision maker consents for patient participation 5. Prisoner or incarcerated or patients held by law enforcement officials in custody 6. Pregnancy or patient refusal for pregnancy testing or screening (standard UTSW policy and protocol requires pregnancy testing for appropriate patients prior to anesthesia)
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What it tests

  • Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2)
  • Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7)
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Where

1 site
Clements University Hospital
Dallas, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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