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International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors

Recruitingn/aAges 18 Years - anyAllAzienda Ospedaliero-Universitaria Careggi
NCT05363657 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Partial nephrectomy (PN) is the standard treatment for localized renal masses and should be preferred in clinical T1 (\<7 cm tumor diameter) renal tumors over radical nephrectomy (RN) whenever technically feasible. Nonetheless, indications, approaches, techniques for PN, and correct reporting of outcomes, are still a matter of great debate within the urology community. Concurrently, case-report series suggested that alternative strategies for the treatment of localized renal tumors (ablation techniques (AT), watchful waiting (WW), active surveillance (AS)) could be feasible with acceptable oncologic outcomes in particular settings of patients with localized renal tumors. In this complex clinical scenario, the role surgeon-related and environmental factors (such as surgical experience, hospital resources, countries' social background and performance of health system) are important to addr

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📋 Eligibility rules (as published)
Inclusion Criteria: * Radiological diagnosis of renal tumor susceptible to active treatment or AS/WW. * Age ≥18 years * Informed consent signed Exclusion Criteria: * Patient refuse to participate in clinical research. * Urothelial renal carcinoma.
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What it tests

  • Partial Nephrectomy (PN)
  • Radical Nephrectomy (RN)
  • Ablation therapy (AT)
  • Active Surveillance (AS)
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Where

37 sites
Institute of Urology, University of Southern California.
Los Angeles, United States
University of California San Diego, Moores Cancer Center
San Diego, United States
Stanford University
Stanford, United States
Loyola University Medical Center, Edward Hines VA Hospital
Chicago, United States
University of Pennsylvania
Philadelphia, United States
VCU Health System
Richmond, United States
Swedish Hospital
Seattle, United States
Medical University of Vienna, Vienna General Hospital
Vienna, Austria

…and 29 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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