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Rice Technologies for Cervical Cancer Screening and Diagnosis

RecruitingNAAges 25 Years - 49 YearsFemaleM.D. Anderson Cancer Center
NCT05372484 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study aims to compare the accuracy of the lateral flow test to detect HPV at the POC with commercially available HPV test and to determine the diagnostic accuracy and reliability of a multimodal optical imaging system to detect cervical dysplasia, with the gold reference standard of histopathology.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. 25 - 49 year old women 2. Women with a positive cervical cancer screening test (abnormal cytology, positive VIA and/or positive HPV test) 3. Women with intact cervix 4. Women who are not pregnant and with a negative pregnancy test (within 14 days from the date of enrollment) ) and not currently breastfeeding 5. Willing and capable of providing informed consent Exclusion Criteria: 1. Women under 25 or over 49 years old 2. Women who have undergone a total hysterectomy (with removal of the cervix) 3. Women who are pregnant or breastfeeding
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What it tests

  • Multimodal optical imaging
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Where

4 sites
M D Anderson Cancer Center
Houston, United States
José Macamo General Hospital and Health Center
Maputo, Mozambique
Maputo Central Hospital
Maputo, Mozambique
Mavalane Hospital and Health Center
Maputo, Mozambique
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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