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Olfactory Training as a Treatment for Olfactory Dysfunction Post COVID-19

RecruitingNAAges 18 Years - anyAllUniversité du Québec à Trois-Rivières
NCT05384561 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Olfactory dysfunction is a defining symptom of COVID-19 infection. Studies have demonstrated improved olfaction in patients with post infectious olfactory dysfunction after an olfactory training (OT). The aim of this study is to assess the clinical outcomes of olfactory training (12 weeks) therapy in the treatment of persistent olfactory dysfunctions after COVID-19. Specially, we aim to compare the effectiveness of two different olfactory training (different odors). A group will train themselves with 4 scents (rose, orange, clove and eucalyptus) and another group with 4 different scents (cheese, coffee, strawberries and lemon). Olfaction sensory evaluation will be performed by using different olfaction tests (Sniffin' Sticks and UPSIT) and complete questionnaires to assess olfactory perception and particularly parosmia and phantosmia.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient diagnosed positive for COVID-19 with persistent olfactory dysfunction * Willing and able to provide written informed consent * Understand and read the French language * Have an internet connection and a working email address Exclusion Criteria: * Anosmia and hyposmia pre-covid-19 * Be known chronic rhinosinusitis with or without nasal polyposis * Have received radiotherapy or chemotherapy for Head and Neck Tumors * Have a diagnosis of Alzheimer's, Parkinson's, multiple sclerosis or any other neurodegenerative disease 5. Have a brain tumor or ENT diagnosis 6. History of naso-sinus surgery; 7. History of traumatic brain injury
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What it tests

  • Smell training
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Where

1 site
Université du Québec à Trois-Rivières
Trois-Rivières, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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