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Electroclinical Correlation of Anxiety

RecruitingNAAges 18 Years - 65 YearsAllUniversity Hospital, Bordeaux
NCT05393518 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Anxiety disorders have the highest prevalence among mental disorders and cause considerable individual and financial costs. Current treatments do not relieve mental suffering of many patients. Understanding neurobiological mechanisms involved in pathological anxiety is a major scientific challenge.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Man or woman * Aged 18 to 65; * With drug-resistant epilepsy * Benefiting from a phase II pre-surgical assessment with intracerebral electrophysiological exploration by stereo-EEG * Meeting the DSM-5 diagnostic criteria for generalized anxiety disorder ("pathological" population) or not meeting the DSM-5 diagnostic criteria for generalized anxiety disorder ("control" population) * WAIS IV full scale IQ \> 75 or IAG \> 81 * Affiliate or beneficiary of a social security scheme * Giving free, informed consent in writing and signed by the participant and the investigator Exclusion Criteria: * Being unable to give personal consent * Be subject to a measure of legal protection (curatorship, guardianship) or placed under judicial protection; * Suffer from a chronic delusional disorder (eg: schizophrenia); * Have a moderate or high risk of suicide assessed using the corresponding section of the structured psychiatric interview called "Mini International Neuropsychiatric Interview" (M.I.N.I. 7.0) or a score \> 2 on item 10 of the MADRS, assessing suicidal risk; * Being pregnant or breastfeeding * Have severe and / or decompensated somatic illness other than drug-resistant epilepsy
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What it tests

  • Anxiety-induced task
  • Neuropsychiatric assessment
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Where

1 site
CHU de Bordeaux
Bordeaux, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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