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โ† Trials
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LIVing Donor Allograft for Anterior Cruciate Ligament Reconstruction Study

RecruitingNAAges 8 Years - 17 YearsAllMaidstone & Tunbridge Wells NHS Trust
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In plain words

What the trial is, and whether it could suit you

The Anterior Cruciate Ligament (ACL) is a major stabiliser of the knee. ACL rupture is being increasingly identified in children and skeletally immature patients. The current advice in younger patients is usually to undergo ACL reconstruction. The choice of an ideal graft in children is difficult This study will use a technique involves the use of hamstring tendons from a living donor, where the adult (usually a parent) agrees to donate their hamstring tendons, which are dissected out of them and implanted into the child

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients aged 8 to 17 years inclusive and have a clinically and radiologically confirmed ACL rupture that requires reconstruction. * Patients who have had previous surgery for meniscal pathology . * Patients with current meniscal pathology * The child and their responsible adult are in agreement with the choice to undergo anterior cruciate ligament reconstruction using living donor allograft. * Donors has not previously undergone tendon harvest on the chosen donor limb * Patients are willing to attend follow up appointments and agree to fill in knee questionnaires and allow instrumented knee ligament testing. Exclusion Criteria: * Patients who have previously undergone ACL surgery on the same limb (and therefore require revision surgery) * Patients who are immunosuppressed, or receiving immunosuppressive therapy * Patients who are unable to attend follow-up appointments for continued research purposes. * Donors who have previously undergone hamstring tendon surgery on the donor limb * Patients and donors who have a positive screening blood test for any of the transmissible infections tested * Donors whose answers to the 'Donor Documentation Questionnaire' indicate that there could be a risk of transmissible infection, may not included * Donors who are not considered healthy enough to undergo a tenotomy under General anaesthetic
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What it tests

  • Endoscopic Anterior Cruciate Ligament reconstruction using living donor hamstring allograft from a parent donor
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Where

1 site
Trauma & Orthopaedic Dept, Tunbridge Wells Hospital
Pembury, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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