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A Natural History Study of Metabolic Sizing in Health and Disease

Recruitingn/aAges 2 Years - 99 YearsAllNational Institute of Diabetes and Digestive and …
NCT05398783 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background: Scientists have long used simple measures (such as height and weight) to estimate how much a person s body uses food (calories) as energy, as commonly called the metabolic rate. But metabolism varies among people with similar body sizes. Scientists now believe the old formulas for estimating metabolic rates may not work well for all people. Researchers want to find more accurate ways to measure a person s metabolism. Objective: This natural history study will examine the relationships between metabolism, body composition, and body surface area in a wide range of people. Eligibility: Healthy children and adults aged 2 years or older. Also, people aged 2 years or older with conditions that may alter metabolism. These may include diabetes, obesity, renal disease, or cancer. Design: Participants will spend 2 days and 1 night in the hospital. They will provide a medical his

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📋 Eligibility rules (as published)
* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all the following criteria for their cohort: Cohort 1 - Healthy Volunteers * Male or female, aged \>=2 years * In good general health as evidenced by medical history Cohort 2 - Patients * Male or female, aged \>=2 years * Diagnosed with diseases thought to alter metabolism or body composition (such as weight loss or gain, diabetes, renal disease, obesity, cancer, etc.) or taking medications thought to alter metabolism or body composition. EXCLUSION CRITERIA: An individual who meets any of the following criteria will be excluded from participation in this study: * Participants over 200 kg due to the weight limit of the equipment. * Presence of any implanted device that would interfere with measurements. * Any moderate to severe limitations in mobility that would impede participation * Hemoglobin less than 10 g/dL (in participants who would have blood drawn for research purposes). * Participants with dietary allergies, intolerances or eating patterns that would preclude them from consuming metabolic meals. * Participants unwilling or unable to give informed consent. * Participants with any other significant physical, medical, or psychiatric limitations, illness or conditions that may preclude them from completing the majority of the tests in this study per the discretion of the PI.
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What it tests

  • Not listed
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Where

1 site
National Institutes of Health Clinical Center
Bethesda, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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