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Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color

RecruitingNAAges 18 Years - anyAllMelissa Pugliano-Mauro
NCT05408117 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at least 3 cm in length will receive each suture type. Measurements of dyspigmentation and scarring will be made at 7 days (for the head and neck), 10 days (for the trunk and extremities), and 3 months for all locations.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age 18 years or older 2. Undergoing dermatologic surgery with planned standard elliptical excision with wound length of 3 cm or greater. Benign and malignant lesions will be included, including those that have undergone Mohs micrographic surgery prior to standard linear closure. All body sites will be included. 3. Able to give informed consent 4. Able to return for 3 month follow up 5. New Immigration Scale (NIS) skin color 4 or greater - The NIS is an 11 point scale, ranging from zero to 10, with zero representing albinism and 10 representing the darkest possible skin. Exclusion Criteria: 1. High-tension closures not amenable to 5-0 simple running epidermal sutures 2. Known allergy to suture material 3. Pregnant
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What it tests

  • 5-0 Polypropylene epidermal suture
  • 5-0 Fast gut epidermal suture
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Where

3 sites
UPMC Presbyterian
Pittsburgh, United States
UPMC St. Margaret
Pittsburgh, United States
UPMC Shadyside Place
Pittsburgh, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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