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PRP in ACLR to Prevent PTOA

RecruitingPhase 3Ages 14 Years - 50 YearsAllHospital for Special Surgery, New York
NCT05412381 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Acute ACL injury within 6 weeks of presentation * Age 14-50 * Male or female * Meniscus injury that can be treated with meniscectomy or repair (the lack of meniscus injury will not exclude patients) Exclusion Criteria: * Prior ACL reconstruction * Prior cartilage repair procedure * Prior meniscus surgery within 12 months * Prior steroid, hyaluronic acid, or PRP injection within 6 months * Other ligament injury requiring repair * Any cartilage lesion requiring repair * Any cartilage lesion greater than grade 2 (partial thickness injury) * History of inflammatory arthritis or joint sepsis * Non English speakers
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What it tests

  • platelet rich plasma (PRP) injection
  • placebo saline injection
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Where

1 site
Hospital for Special Surgery
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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