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Inhaled Isopropyl Alcohol for Treatment of Nausea

RecruitingPhase 2, Phase 3Ages 7 Years - 17 YearsAllState University of New York at Buffalo
NCT05418244 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with a chief complaint of nausea or vomiting * Ages 7-178 years, both sexes * Weight ≥ 15 kg * Baxter Animated Retching Faces (BARF) nausea severity score ≥ 4/10 Exclusion Criteria: * 1\. Require IV access * Inability to breathe in/out through the nose * Anosmia (self- or parental report) * Allergy to isopropyl alcohol or ondansetron * Current or history of alcohol abuse * Inability to communicate feeling nauseous * Inability to follow directions regarding taking deep breaths through the nose * Known prolonged QT interval * Pregnancy * Received antiemetics within the last 8 hours * Currently taking apomorphine
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What it tests

  • Inhaled Isopropyl Alcohol
  • Oral Ondansetron
  • Inhaled Placebo
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Where

1 site
Oishei Children's Hospital
Buffalo, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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