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Risk Factors and Biomarkers for Post-tuberculosis Lung Damage

Recruitingn/aAges 25 Years - 60 YearsMalePeking University Third Hospital
NCT05426720 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective study aims to determine the incidence of Post-tuberculosis lung damage (PTLD), examine trends in the changes in lung function, and investigate the impact of smoking and other factors on respiratory symptoms, lung function, and chest CT findings, which will aid in the development of prognostic and therapeutic strategies for PTLD.

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📋 Eligibility rules (as published)
Inclusion Criteria: Male patients aged 25-60 years newly diagnosed with active pulmonary TB. Exclusion Criteria: 1. patients with positive sputum smear or TB culture results; 2. human immunodeficiency virus-positive patients; 3. patients infected with multidrug-resistant TB; 4. patients with malignant neoplasms (e.g., lung cancer) or severe cardiovascular and cerebrovascular diseases; 5. non-compliant patients who were unable to complete the lung function tests; 6. patients without lung parenchymal destruction (such as tuberculous pleurisy). -
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What it tests

  • no intervention
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Where

2 sites
Peking University Third Hospital
Beijing, China
Beijing Geriatric Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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