AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

RecruitingNAAges 18 Years - anyAllUniversity of Texas at Austin
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided respiratory intervention (CGRI) for pathological anxiety. CGRI aims to raise end-tidal CO2 levels thereby lowering hyperventilation-induced respiratory alkalosis and its associated fear-eliciting somatic reactions. Psycho-education about anxiety and its effects (PsyEd) will serve as a credible control comparator.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Clinically elevated anxiety as indicated by an eight or higher on the Overall Anxiety Severity and Impairment Scale (OASIS). 2. Meets DSM-5 criteria for one or more of the following anxiety or trauma-related disorders as their "primary" mental disorder: * Generalized Anxiety Disorder * Panic Disorder * Health Anxiety * Agoraphobia * Social Anxiety Disorder * Posttraumatic Stress Disorder * Acute Stress Disorder * Adjustment Disorder with primary anxious mood * Anxiety disorder not otherwise specified 3. No current use of psychotropic medications or stable on current medications for at least 6 weeks 4. Age 18+. 5. Able to arrange transportation to our laboratory for study appointments. 6. Fluent in English. Exclusion Criteria: 1. No history of medical conditions that would contraindicate participation in fear-provocation or respiratory challenges, including: * Cardiovascular or respiratory disorders * High blood pressure * Epilepsy * Strokes * Seizures * History of fainting * Pregnant or lactating 2. Not currently receiving other psychological treatment for anxiety. 3. No history of a suicide attempt within the past 6 months. 4. No history of psychosis within the past 6 months. 5. No history of moderate to severe alcohol or substance use disorder (with the exception of nicotine) within the past 3 months. 6. Does not endorse COVID-19 symptoms during the screening phase.
๐Ÿ’Š

What it tests

  • Capnometry-Guided Respiratory Intervention
  • Psycho-Education
๐Ÿ“

Where

1 site
University of Texas at Austin
Austin, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy