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Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging

Recruitingn/aAges 18 Years - anyAllR&D Cardiologie
NCT05432024 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities. This study uses cardiovascular magnetic resonance imaging to evaluate the ablation lesion characteristics of radiofrequency ablation, ultra-low temperature cryo ablation, and pulsed field ablation. The ablation lesion characteristics of different energy characteristics will be compared. Additionally, arrhythmia recurrence and quality of life will be evaluated for the different energy modalities.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients (age ≥18 years old) * Paroxysmal or persistent atrial fibrillation, meeting criteria of the 2020 European Society of Cardiology Guidelines for diagnosis and management of atrial fibrillation * Patients scheduled to undergo catheter ablation for cardiac arrhythmia using one of the following techniques: Radiofrequency ablation (High power, short duration), Ultra-low temperature cryo ablation, or Pulsed field ablation Exclusion Criteria: * Known (or suspected) allergic reaction to gadolinium * Contraindications for MRI (such as claustrophobia, certain implants, devices, high body mass index). * Pregnancy or breastfeeding * Prior intervention in the left atrium (ablation or surgery)
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What it tests

  • Catheter ablation
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Where

1 site
St. Antonius Hospital
Nieuwegein, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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