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Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy

RecruitingNAAges 18 Years - anyAllUniversity of Manitoba
NCT05433129 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The investigators propose to employ advanced multi-channel near non-invasive near infrared spectroscopy (NIRS) system married with entirely non-invasive continuous arterial blood pressure (niABP) monitor to create a new wearable and portable imaging system that derives CA maps of the entire brain with high sampling rates at each point. The objectives of this project are as follows: 1. To perform in vivo testing and optimization of the device using a block-trial design to evaluate the CA mapping system's performance during various perturbations. 2. To explore the impact of aging and sex on regional disparities in CA in a healthy volunteer population using static recording along with perturbation testing.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy volunteers (male and female) * Age \> 17 Exclusion Criteria: * History of neurological illness * History of systemic vascular * History of cerebrovascular disease
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What it tests

  • Transient hyperemic response
  • Orthostatic challenge
  • Vascular chemo-reactivity
  • Neurovascular coupling
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Where

1 site
Health Sciences Centre (HSC)
Winnipeg, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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