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โ† Trials
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Modulating Exercise Dosage to Improve Concussion Recovery

RecruitingPhase 1, Phase 2Ages 13 Years - 18 YearsAllUniversity of Colorado, Denver
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In plain words

What the trial is, and whether it could suit you

Aerobic exercise has emerged as an effective treatment to reduce sport-related concussion symptom severity, yet existing work lacks rigor regarding the precise exercise volume and intensity required to elicit therapeutic effects, how exercise can alter concussion-related pathophysiology, and whether exercise can prevent the development of secondary sequelae. Our objective is to examine if a high dose exercise program (higher volume than currently prescribed at an individualized, safe intensity level) initiated within 21 days of concussion results in faster symptom resolution, altered physiological function, or reduced secondary sequalae. Findings from this research will lead to more rigorous and precise rehabilitation guidelines and improved understanding about how exercise affects neurophysiological function among adolescents with concussion.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * 13-18 years of age * Post-Concussion Symptom Scale (PCSS) score \>10 to ensure participants are not recovered by enrollment * Concussion diagnosis by a sports medicine physician Exclusion Criteria: * Pre-existing neurological disorders * Exercise contraindications * Concussion \<6 months before enrollment (excluding the current injury)
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What it tests

  • High Dose Exercise
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Where

3 sites
University of Colorado Denver
Aurora, United States
Boston Children's Hospital
Boston, United States
Spaulding Rehabilitation Hospital
Cambridge, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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