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Surgical Ablation of AF Efficacy Trial

RecruitingNAAges 18 Years - anyAllPopulation Health Research Institute
NCT05434819 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

SAFE is an international multicentre RCT of concomitant surgical atrial fibrillation (AF) ablation in patients with paroxysmal or persistent AF undergoing cardiac surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years; * Undergoing a clinically indicated cardiac surgical procedure: CABG, AVR, ascending aorta replacement, or combinations thereof; * Documented history of paroxysmal or persistent AF * Provide informed consent Exclusion Criteria: * Dominant atrial arrhythmia is atrial flutter; * Documented left atrial diameter ≥ 6 cm; * Previous cardiac surgery requiring opening of the pericardium; * Patients undergoing any of the following procedures: 1. Heart transplant 2. Complex congenital heart surgery 3. Sole indication for surgery is ventricular assist device insertion 4. Mitral valve repair or replacement 5. Tricuspid valve repair or replacement * Patient resides in a long-term care facility
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What it tests

  • Surgical Atrial Fibrillation Ablation
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Where

1 site
Hamilton General Hospital
Hamilton, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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