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Preoperative Corticosteroids in Autoimmune Thyroid Disease

RecruitingPhase 4Ages 18 Years - anyAllIndiana University
NCT05435547 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of the gland and makes surgery less difficult.

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📋 Eligibility rules (as published)
* Inclusion Criteria: ■ Graves' disease or Hashimoto's disease with positive thyroid autoantibodies (TgAb, TPO, TSI, and/or TRAb) undergoing total thyroidectomy for their disease. * Exclusion Criteria: * Pediatric patients \< 18 * Prior treatment with RAI * Prior neck surgeries * Known diagnosis of thyroid cancer * Diabetic patients on medications * A history of adverse reactions to corticosteroids. * Patients on any immunosuppressive regimen (such as organ transplant patients or patients treated for other autoimmune conditions). This includes patients with recent history of steroid therapy, or a history of adverse reactions to corticosteroids.
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What it tests

  • Dexamethasone
  • Placebo
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Where

3 sites
IU Health North Hospital
Indianapolis, United States
IU Health Methodist Hospital
Indianapolis, United States
IU Health University Hospital
Indianapolis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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