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Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

Recruitingn/aAges 4 Years - 35 YearsFemaleEunice Kennedy Shriver National Institute of Chil…
NCT05440617 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background: Medical advances have improved survival rates for many cancers and other illnesses. This means that more people are coping with the long-term effects of these treatments. Some treatments can cause female infertility. Ovarian tissue cryopreservation (OTC) may help. Before undergoing a treatment that may damage their fertility, patients may opt to freeze a sample of ovarian tissue. The tissue contains immature egg cells. When thawed, the tissue can be reimplanted. This procedure can help women become pregnant. Objective: This natural history study will create a databank of ovarian tissue. The NIH will provide OTC as a clinical service. The NIH will also request a portion of the tissue to use for research. Eligibility: Females aged 4 to 35 who opt to have OTC before receiving cancer treatment. Design: Participants will be screened. Their existing medical records will be r

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📋 Eligibility rules (as published)
* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Provision of signed and dated informed consent/assent form. * Stated willingness to comply with all study procedures and availability for the duration of the study. * Subjects who have planned to undergo OTC for gonadotoxic therapy based on current standard of care. EXCLUSION CRITERIA: -An individual who meets any of the following criteria will be excluded from participation in this study: --Adults subjects with psychological, psychiatric, or other conditions which prevent giving fully informed consent.
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What it tests

  • Not listed
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Where

1 site
National Institutes of Health Clinical Center
Bethesda, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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