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Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Escalation in Young Adult ENDS Users

RecruitingNAAges 18 Years - 29 YearsAllUniversity of Georgia
NCT05447325 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

180 young adult vapers who are not current smokers will participate in a baseline functional magnetic resonance imaging (fMRI) experiment, prospectively linked to a 1-year randomized controlled trial. Baseline fMRI tasks will probe critical neurocognitive markers with high potential to account for individual differences in nicotine use prognosis and responsiveness to anti-vaping public service announcements (PSAs). Participants will be assigned randomly to a survey-only control condition, or one of two intervention orders, Regular PSA then Flavor PSA, and Flavor PSA then Regular PSA (n=60 each) in a 1-year counterbalanced crossover design. Every week intervention groups will receive anti-vaping PSAs either do not specifically address harms associated with vaping flavors (regular PSAs) or PSAs with a theme focusing on the harms of flavored vape products (flavor PSAs). Participants of the

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📋 Eligibility rules (as published)
Inclusion Criteria: * used e-cigarettes or other vaping devices at least 3 days during the past 30 days * did not smoke a cigarette, even one or two puffs, during the past 30 days * Magnetic resonance imaging (MRI) compatible and safe Exclusion Criteria: * used e-cigarettes or other vaping devices for less than 3 days during the past 30 days * any use of cigarettes during the past 30 days * history of a major neurological, psychiatric, or medical disorder * MRI contraindications
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What it tests

  • Exposure to Anti-Vaping Messages (generic themes then flavor-specific themes)
  • Exposure to Anti-Vaping Messages (flavor-specific themes then generic themes)
  • Exposure to Anti-Vaping Messages (no message exposure)
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Where

1 site
UGA Bio-imaging Research Center
Athens, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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