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Evaluation of Clinical Outcomes of Unruptured bAVMs Treated With Medical Management Alone Based on Multimodal CT

Recruitingn/aAges 3 Years - 80 YearsAllBeijing Tiantan Hospital
NCT05449106 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to investigate the role of multimodal CT in evaluating and predicting different clinical outcomes in patients with unruptured brain arteriovenous malformations with medical management alone. This study will be undertaken in the following aspects: 1. Morphological, structural and imaging histological signal analysis based on multimodal CT to explore the relationship between imaging features and different clinical outcomes of bAVMs. 2. Hemodynamic and flow pattern analysis of local and peripheral bAVMs based on multimodal CT to explore the association between blood flow features and different clinical outcomes. 3. Based on multimodal CT and deep learning algorithms to create an automated segmentation model for bAVMs and a prediction model for distinct clinical outcomes. The obtained patient information includes: Baseline information, CT, MRI, DSA (Optional),

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients with confirmed diagnosis of brain arteriovenous malformations in the brain, basal ganglia, thalamus, corpus callosum, cerebellum and other locations. 2. Patients with no history of previous arteriovenous malformation-related hemorrhage and no arteriovenous malformation-related hemorrhage confirmed by CT examination. 3. Patients with Radiographic examinations completed without any treatment Exclusion Criteria: 1. Patients with simple arteriovenous fistula. 2. Patients with combined dural arteriovenous fistulas. 3. Arteriovenous malformations occurring in the spinal cord. 4. Pregnant patients were not included in this study.
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What it tests

  • Not listed
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Where

4 sites
Beijing Tiantan Hospital, Capital Medical University
Beijing, China
Beijing Hospital
Beijing, China
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, China
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Nanjing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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