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Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion

RecruitingPhase 1Ages 18 Years - anyAllUniversité de Sherbrooke
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In plain words

What the trial is, and whether it could suit you

The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis. These patients usually have severe intractable facial pain and current medical and surgical options generally fail to achieve long lasting pain relief. Hoping to improve pain control in this population, the investigators of this trial propose a novel technique consisting of implanting a deep brain stimulation lead within the pontine lesion to modulate the generation of pain signals.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults of at least 18 years old * Refractory trigeminal neuralgia : failure of at least 3 drugs and at least two lesioning surgical interventions (radiosurgery, percutaneous rhizotomy, or open rhizotomy). * Pontine lesion proved by MRI in contact with trigeminal nerve tract Exclusion Criteria: * Absolute contraindication to MRI * Medical contraindication to the procedure
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What it tests

  • Deep brain stimulation
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Where

1 site
Centre Hospitalier Universitaire de Sherbrooke (CHUS)
Sherbrooke, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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