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Mental Health Crises in Youth With IDDs

Recruitingn/aAges 7 Years - 17 YearsAllRady Pediatric Genomics & Systems Medicine Instit…
NCT05471232 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is an unmatched, case-control study of 150 youth (Ages 7-17) with a parent reported Intellectual Developmental Disability (IDD) who present to Rady Children's Hospital Emergency Department with a Mental Health Crisis (MHC). Rady Children's Institute for Genomic Medicine (RCIGM) will collect biological samples (such as blood) of these participants to study their genomes, medical and psychiatric profiles to better understand specific characteristics that may predispose them to MHC's. The 150 youth will be compared to historical, publicly available cohorts of youth with IDD's

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📋 Eligibility rules (as published)
Inclusion Criteria: Child/adolescents admitted to the RCHSD ED with an IDD presenting in a MHC that includes, but is not limited to: * Aggression towards others * Severe agitation * Self-injury * Elopement OR Biological parents of child/adolescent enrolled in this study for the purposes of reflex testing. (Family members are eligible for participation in this study if they presumed genetically related to a participant). Exclusion Criteria: Child/Adolescents participants who do not meet any of the inclusion criteria, or those who: * Already received any prior whole genome sequencing or exome sequencing * Unable to approach the family or patient for enrollment * Unable to obtain informed consent * family members are ineligible for participation in this study if they are known to not be genetically related to the child/adolescent participant and/or if they are a member of a protected research population.
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What it tests

  • Genomic sequencing and molecular diagnostic results, if any.
  • EHR-Based Network Model
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Where

1 site
Rady Children's Hospital San Diego
San Diego, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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