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Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity

Recruitingn/aAges 18 Years - 100 YearsAllPhilip Polgreen
NCT05474430 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to perform our functional respiratory assays. An individual trained in phlebotomy will draw one 3 ml lavender top tube of blood to test c-reactive protein, calprotectin, and lactoferrin. They will also draw a 5 ml gold top serum separator tube of blood to test fibroblast growth factor-19. The participant will answer questions from the baseline survey and report their current medications interview-style with the research team member.

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📋 Eligibility rules (as published)
CF Carrier Inclusion Criteria: * Previously tested and shown to be a CF carrier * English-speaking Control Group Inclusion Criteria: * Previously tested and shown to not be a CF carrier or CF patient * English-speaking Exclusion Criteria: * Currently sick with a respiratory infection * Prisoner Status * Unable to provide own written, informed consent
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What it tests

  • Not listed
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Where

1 site
University of Iowa Hospitals and Clinics
Iowa City, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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