🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Concurrent Fluorescence and Sonographically Guided Eradication of High-grade Gliomas and Metastases

RecruitingNAAges 18 Years - 80 YearsAllSklifosovsky Institute of Emergency Care
NCT05474573 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The objective of the study is to determine whether the combined use of intraoperative fluorescence with 5-aminolevulinic acid (5-ALA) and sonography can achieve a higher rate of gross total resection in hemispheric high-grade gliomas and brain metastases compared to intraoperative fluorescence with 5-ALA alone.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * single high-grade glioma * solitary, single or multiple brain metastases of solid tumors of any primary origin * newly diagnosed * Karnofsky Performance Status 60-100% * age 18-80 years * performed magnetic resonance imaging with contrast enhancement * intraoperative use of 5-aminolevulinic acid induced fluorescence. Exclusion Criteria: * tumor spreading to corpus callosum or brainstem * history of brain tumor radiotherapy * planned supratotal tumor resection (until neurophysiologically revealed eloquent areas) * known hypersensibility to 5-aminolevulinic or to porphyrin * hepatic or renal insufficiency * porphyria * pregnancy * breast feeding
💊

What it tests

  • Combined ultrasound and fluorescence-guided brain tumor resection
  • Fluorescence-guided brain tumor resection
📍

Where

1 site
Sklifosovsky Institute of Emergency Care
Moscow, Russia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy