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Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

RecruitingNAAges 18 Years - anyAllMedical University of South Carolina
NCT05492188 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain. For this, the researchers are recruiting 15 individuals with neuropathic pain due to spinal cord injury to participate in the reflex training procedure. The study involves approximately 50 visits with a total study duration of about 6.5 months (3 months for baseline and training phases followed by 1 month and 3 month follow-up visits).

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. neurologically stable (\>1 year post SCI) 2. medical clearance to participate 3. ability to stand with or without an assistive device for at least 3 minutes at a time 4. expectation that current medication will be maintained without change for at least 3 months (stable use of anti-spasticity medication is accepted) 5. For participants with neuropathic pain, the area of neuropathic pain must include lower leg. Exclusion Criteria: 1. motoneuron injury 2. known cardiac condition 3. medically unstable condition (incl. pregnancy) 4. cognitive impairment 5. uncontrolled peripheral neuropathy 6. frequent use of electrical spinal stimulation (either transcutaneous or epidural) for pain treatment 7. daily use of electrical stimulation to the leg 8. complete lack of cutaneous sensation around foot.
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What it tests

  • Operant Conditioning of Cutaneous Reflexes
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Where

1 site
Medical University of South Carolina
Charleston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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