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The Heartland Study

Recruitingn/aAges 18 Years - anyFemaleHeartland Health Research Alliance
NCT05492708 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. The study is being conducted to evaluate the associations between environmental exposures to herbicides during and after pregnancy and reproductive health outcomes. The study is measuring multiple biomarkers of herbicide exposure among pregnant Midwesterners and their partners to evaluate associations with pregnancy and childbirth outcomes, epigenetic biomarkers of exposure, and child development.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Pregnant persons ages 18 or older at time of consent who are ≤20+6 weeks pregnant. Best clinical estimate of gestational age will be utilized for recruitment purposes. Enrollment in the first trimester (≤ 13 + 6) is preferred, but anyone ≤ 20 +6 is permitted. * Living in one of the 13 Heartland Study region states at the time of enrollment (Arkansas, Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, or Wisconsin) Optional inclusion of the putative biological father Exclusion Criteria: * Participants who are not fluent in and/or do not fully understand, read, write, or speak the English language. * Other inability to provide informed consent to participate
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What it tests

  • Not listed
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Where

4 sites
Indiana University Medical Center
Indianapolis, United States
University of Iowa Health Care
Iowa City, United States
Gundersen Health
La Crosse, United States
Marshfield Clinic
Marshfield, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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