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Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

RecruitingEARLY Phase 1Ages 18 Years - anyAllUniversity of Minnesota
NCT05493722 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.

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📋 Eligibility rules (as published)
Inclusion Criteria: * medically refractory epilepsy * already have a deep brain stimulator in place Exclusion Criteria: * severe dementia at investigator discretion
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What it tests

  • Physician-Selected Settings Stimulation
  • Optimized Settings Stimulation
  • DBS Setting Optimization
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Where

1 site
University of Minnesota
Minneapolis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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