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Specific Dietary Pattern for Crohn's Disease Patients Following Surgery

RecruitingNAAges 14 Years - anyAllSecond Affiliated Hospital, Zhejiang University, …
NCT05502965 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Over the past 10 years, there are a large number of dietary treatments related to the CD, such as specific carbohydrate diet, low Fermentable Oligo-, Di-, Mono-saccharides And Polyols (FODMAP) diet, and allergen-free foods. But there is no consistent conclusion or convincing evidence about the effectiveness. Through the long-term clinical experience observation, we find most of the CD patients can get stable remission by removing refined food and intolerance food.This project aims at developing a new dietary therapy suitable for Chinese patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Diagnose CD according to endoscopy, histology and imaging; 2. Bowel resection for CD 3. Oral nutritional preparations or food can be given after surgery Exclusion Criteria: 1. Plan operation within 5 weeks after surgery; 2. Presence of an ileostomy or colostomy 3. Complete bowel obstruction or fibrous stricture 4. Pregnancy or breastfeeding; 5. Plan to use biological agents within 5 weeks after surgery; 6. Plan to use corticosteroids or prednisone greater than 20 mg per day or equivalent doses of drugs to maintain remission within 5 weeks after surgery; 7. Plan to use probiotics or prebiotics for more than 1 week after surgery; 8. Antibiotics are used for more than 2 weeks after surgery; 9. Hypersensitivity to known components of enteral nutrition; 10. BMI less than 14 or greater than 28 kg/m2; 11. Celiac disease; 12. Complicated with other autoimmune diseases such as diabetes or rheumatic disease, autoimmune liver disease, psoriasis; 13. Mental illness; 14. Malignant tumors 15. Those who are not suitable for body composition analysis (such as pacemakers and metal objects in the body) 16. Participating in other clinical trials 17. The researcher believes that others are not suitable to participate in this study.
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What it tests

  • dietary pattern
  • EEN
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Where

1 site
2nd Affiliated Hospital, School of Medicine, Zhejiang University
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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