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Timing of Soft Tissue Grafting Following Immediate Implant Placement

RecruitingNAAges 20 Years - anyAllUniversity Ghent
NCT05537545 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT). Prior to surgery, a small- field low-dose cone beam computed tomography (CBCT) is taken to verify the integrity of the facial bone wall and an adequate amount of apical and palatal bone availability for implant anchorage. In all of the patients, a connective tissue graft (CTG) will be harvested and inserted into the buccal mucosa to increase soft tissue thickness around the immediately installed implant. However, included patients will be randomly allocated to either receive the CTG immediately after implant installation (Immediate soft tissue grafting, ISG = control group) or 3 months after implant installation (Delayed soft tissue grafting, DSG = test group). Forty sealed envelopes are prepared for that purpose, of which 20 are inter

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📋 Eligibility rules (as published)
Inclusion Criteria: * At least 20 years old * Good oral hygiene defined as full-mouth plaque score ≤ 25% (O'Leary et al. 1972) * Presence of an incisor, cuspid or premolar in the maxilla that needs to be extracted for any reason with at least one neighboring tooth present * At least 3 mm bone available at the apical or palatal aspect of the alveolus as assessed on CBCT to ensure primary implant stability * Intact buccal bone wall at the time of extraction * Written informed consent Exclusion Criteria: * Pregnancy * Systemic diseases * Smoking * Suppuration * \> 1 mm gingival asymmetry between the failing and contralateral tooth * Untreated periodontal disease; untreated caries lesions
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What it tests

  • Soft tissue grafting
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Where

1 site
Ghent University
Ghent, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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