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Tuberculosis Cohort Avicenne Hospital

Recruitingn/aAges 18 Years - 80 YearsAllAssistance Publique - Hôpitaux de Paris
NCT05539014 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Tuberculosis represents the second highest death rate from an infectious disease in the world, just after COVID-19. The most affected department of France is Seine-Saint-Denis. Since 2005, this department with difficult socio-economic conditions has the highest incidence rate in metropolitan France, higher than that of Paris. In 2012, the reporting rate was 10 times higher among people born abroad compared to those born in France, with the highest rates found among people born in sub-Saharan Africa and Asia. It is proposed to constitute for the first time in France a cohort of patients with tuberculosis disease to better understand the characteristics of patients with unfavorable treatment outcomes and ultimately, to propose solutions to obtain better control of tuberculosis. This study would recruit all patients with tuberculosis disease for at least 4 years associated with 1 year of f

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📋 Eligibility rules (as published)
Inclusion Criteria: * Tuberculosis out- or in-patient newly treated in one of the inclusion centers for pulmonary or extra-pulmonary * Tu confirmed bacteriologically (direct examination, Gen-eXpert MTB/RIF and/or positive culture), suggestive histology (epithelioid gigantocellular granuloma with or without caseous necrosis), or strong clinical suspicion of tuberculosis, even if not yet biologically confirmed but with * A decision to introduce treatment. Exclusion Criteria: * opposition to participate in the study, anti-tuberculosis treatment for more than 7 days at the inclusion visit and participation in another research protocol.
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What it tests

  • Data collection
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Where

2 sites
Hopital Avicenne
Bobigny, France
Hôpital Avicenne
Bobigny, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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