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Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries

RecruitingNAAges 19 Years - 60 YearsAllMansoura University
NCT05543785 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries. From the previous documented effectiveness and safety of intravenous (IV) administration of ketorolac in the circulatory-isolated limb as a part of intravenous regional anesthesia; we hypothesized that in orthopedic surgeries done with tourniquet, intravenous (IV) administration of ketorolac after tourniquet inflation, will act as intravenous regional analgesia. So, it will prolong the postoperative analgesic duration as a primary outcome.

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📋 Eligibility rules (as published)
Inclusion Criteria: * American Society of Anesthesiologists physical status I or II * Elective unilateral lower limb orthopedic surgery with tourniquet under spinal anesthesia Exclusion Criteria: * Pregnant females * Body mass index ≥ 35 kg/m2 * Allergy to ketorolac * Had renal, asthmatic, vascular (Raynaud's syndrome) disease, hematological anemias * Had any history of gastrointestinal tract inflammation, bleeding, ulceration, or perforation besides * Edema in the operated limb grade ≥ 3
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What it tests

  • Ketorolac
  • Control
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Where

1 site
Mansoura University Hospitals
Al Mansurah, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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