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Study of SGR-1505 in Mature B-Cell Neoplasms

RecruitingPhase 1Ages 18 Years - anyAllSchrödinger, Inc.
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate safety and tolerability and to determine the maximum tolerated dose (MTD) or maximum administered dose (MAD) and/or recommended dose (RD) of SGR-1505.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Subject must have a history of histologically or cytologically confirmed mature B-cell malignancy. * Subject must have measurable or detectable disease according to the applicable disease-specific classification system and meet criteria for initiation of treatment. * Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1. * Life expectancy ≥ 12 weeks. Exclusion Criteria: * The subject is in need of immediate cytoreductive therapy (unless the patient has no remaining treatment choice with potential benefit). * Subject has previous invasive malignancy in the last 2 years. * Subject has a known allergy to SGR-1505 or excipients of SGR-1505. * Subject has symptomatic or active CNS involvement of disease. * Any other diseases, metabolic dysfunction, physical examination finding, or clinical laboratory finding that would place the participant at increased risk to the use of an investigational drug.
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What it tests

  • SGR-1505
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Where

36 sites
Banner Health - MD Anderson Cancer Center
Gilbert, United States
Christiana Care Hospital - Helen F Graham Cancer Center
Newark, United States
Napa Research
Pompano Beach, United States
Beth Israel Deaconess Medical Center
Boston, United States
Regional Cancer Care Associates
Hackensack, United States
Roswell Park Comprehensive Cancer Center
Buffalo, United States
Weill Cornell
New York, United States
Montefiore Medical Center
The Bronx, United States

…and 28 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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