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Evaluation of the Effectiveness of Virtual Reality Self-rehabilitation in the Treatment of Facial Paralysis and Synkinesis

RecruitingNAAges 18 Years - anyAllCentre Hospitalier Universitaire, Amiens
NCT05547152 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Peripheral facial palsy affects 15 to 40 people per 100,000 inhabitants and induces important functional and social repercussions. Synkinesis is a frequent after-effect of facial palsy recovery, consisting of involuntary facial spasms that disturb the gestural harmony and can go as far as a painful hypertonic spasm. More than 55% of patients recovering from facial palsy will develop transient or permanent synkinesis. These facial hypertonias have two main causes: imperfect axonal regeneration, which is all the more important as the damage is proximal, and hyperexcitability of the facial nerve nucleus due to a lack of central control. Management is therefore essential for the functional restoration of the face, especially since synkinesis do not evolve spontaneously. The main treatments are currently botulinum toxin injection, acting on the motor plate, and functional rehabilitation, cons

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient with recent onset peripheral facial palsy (≤ 12 months). * Patient with peripheral facial palsy of grade ≥ III on the House \& Brackmann score * Patient of legal age (≥ 18 years) * Patient with appropriate information and informed consent Exclusion Criteria: * Patient with central facial palsy * Patient with peripheral facial palsy of \> 12 months onset * Patient with peripheral facial palsy of grade \< III House \& Brackmann score * Patient who has previously undergone palliative surgery * Patient undergoing a botulinum toxin injection protocol * Patients benefiting from enhanced protection, i.e. minors, persons deprived of their liberty by a judicial or administrative decision, persons staying in a health or social institution, adults under legal protection, pregnant or breast-feeding women and patients in emergency situations * Patients who have not provided informed consent * Patients with cognitive disorders that do not allow them to follow the proposed self-education protocol * Blind or visually impaired patients (visual acuity of the better eye after correction ≤ 4/10)
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What it tests

  • massages
  • motor stimulation and stretching
  • virtual reality
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Where

1 site
CHU Amiens Picardie
Amiens, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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