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Safest Choice of Antihypertensive Regimen for Postpartum Hypertension

RecruitingPhase 3Ages 18 Years - anyFemaleLoma Linda University
NCT05551104 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this investigator-initiated randomized control trial is to determine whether oral Nifedipine versus oral Labetalol is superior in controlling high blood pressures in the postpartum period.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female * Women who develop postpartum hypertension\* after delivery of the placenta or chronic hypertensive postpartum women who require medication for blood pressure control. * Postpartum hypertension requiring treatment are defined as systolic blood pressure greater than or equal to 140mmHg or diastolic blood pressure greater than or equal to 90mmHg on at least 2 occasions at least 4 hours apart, or systolic blood pressure greater than or equal to 160mmHg or diastolic blood pressure greater than 110mmHg sustained for more than 15 minutes. Exclusion Criteria: * History of moderate persistent asthma, coronary artery disease, heart failure, AV heart block, pulmonary edema * Contraindication to either Nifedipine or Labetalol * HR \<60 or \>110 * Native language other than English or Spanish
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What it tests

  • Oral Nifedipine
  • Oral Labetalol
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Where

1 site
Loma Linda University Health
Loma Linda, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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