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Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women At Higher Risk

RecruitingPhase 3Ages 18 Years - anyFemaleLondon School of Hygiene and Tropical Medicine
NCT05562609 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Heavy bleeding after childbirth, known as a postpartum haemorrhage (PPH), causes about 70,000 maternal deaths every year. Tranexamic acid (TXA) is a lifesaving treatment for women with PPH. The I'M WOMAN trial is a research study to see whether giving TXA just before childbirth will stop women developing PPH. The trial will assess the effects of intramuscular (IM) and intravenous (IV) tranexamic acid on PPH, side effects and other important maternal health outcomes.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Women aged 18 years or older who are admitted to hospital to give birth vaginally or by caesarean section, who have one or more known risk factors for PPH Exclusion Criteria: * Women who have a clear indication or contraindication for TXA
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What it tests

  • Tranexamic acid
  • Placebo
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Where

1 site
Mbeya Regional Referral Hospital
Mbeya, Tanzania
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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