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A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases

RecruitingNAAges 18 Years - 80 YearsAllAttikon Hospital
NCT05564949 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The survival interval of patients with gliomas ranges between 12 to 15 months. Recent findings revealed that dietary interventions to reduce glucose and glycolytic pathways could have a therapeutic effect. Ketosis can be an effective therapy to extend the survival of patients with gliomas.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18-80 * Karnofsky Performance Score of 50 or more. * Newly diagnosed, histologically confirmed glioblastoma grade 4, or secondary metastases or progression after surgical resection, radiation and chemotherapy. * Normal function of liver and kidneys * Ability to sign informed consent form Exclusion Criteria: * Diabetes mellitus * Life expectancy \>3 months * Inability to adhere to diet * Inability to give informed consent form * Cholecystectomy last 1 year (before the study entry) * Diagnosis of genetic disorder of fat metabolism
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What it tests

  • CKD
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Where

2 sites
Arezina Kasti
Chaïdári, Greece
Attikon University General Hospital
Athens, Greece
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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