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Multicentric Study on Clopidogrel Resistance in DAPT for CAS (MULTI-RESCLOSA)

Recruitingn/aAges 18 Years - anyAllIRCCS Policlinico S. Donato
NCT05566301 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Spontaneous prospective observational multicentre pharmacological study that aims to evaluate whether, from a statistical point of view, there is a significant difference between the use of Ticagrelor in "non-responders" patients to Clopidogrel undergoing carotid stenting and Clopidogrel in "responders" undergoing carotid stenting, in the onset of death and major adverse cardiovascular events (MACE) and bleeding events, 1 and 3 months after the procedure. Furthermore, the study aims to evaluate the possible preoperative clinical and pharmacological factors most associated with the phenomenon of resistance to Clopidogrel. Inclusion criteria: The data will be collected on adult patients (age\> 18 years) who have given their consent to participate in the study, belonging to the U.O. of Vascular Surgery of the IRCCS Policlinico San Donato and the U.O. of Vascular Surgery of the participati

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📋 Eligibility rules (as published)
Inclusion Criteria: * adult patients (age\> 18 years) * patients who have given their consent to participate in the study, belonging to the U.O. of Vascular Surgery of the IRCCS Policlinico San Donato and the U.O. of Vascular Surgery of the participating centers and subjected to the treatment of carotid stenosis by stenting technique. Exclusion Criteria: * underage patients * patients who have not given their consent to participate in the study, * patients who have carotid stenosis not susceptible to intervention by stenting * pregnant or lactating women (such as situations in which carotid stenting is contraindicated regardless of the execution of the study).
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What it tests

  • Clopidogrel
  • Ticagrelor
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Where

1 site
IRCCS Policlinico San Donato
San Donato Milanese, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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