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Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis

RecruitingNAAges 50 Years - 65 YearsFemaleCentre Hospitalier Universitaire de Saint Etienne
NCT05571514 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Post-menopausal osteoporosis and the resulting fractures are an important cause of disability and loss of independence. They also increase the risk of morbidity and mortality. Given potential side effects, hormone replacement therapy is no longer recommended for menopausal women with risk of becoming osteoporotic. The very significant decrease in the use of these treatments is suspected of contributing to a resurgence in the incidence of osteoporotic fractures, particularly in women before the age of 70. There is a need for prevention of osteoporosis.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Post-menopausal women (50-65y) with risk of becoming osteoporotic * T-score between -1 and -3 * Absence of fragility fractures history Exclusion Criteria: * absence of parathyroid glands (phospho-calcic regulation) * presence of kidney stones * patients who follow a treatment that could interfere with bone metabolism (corticotherapy, menopausal hormonal therapy, anti-oestrogen treatment, non-controlled hyperthyroiditis, hyper- and hypothyroiditis) * bone diseases (Paget'disease, osteomalacia) * chronic alcoholism
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What it tests

  • Mother-of-pearl
  • Calcium Carbonate
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Where

7 sites
Hôpital Gabriel Montpied
Clermont-Ferrand, France
Clinique Universitaire de Rhumatologie
Grenoble, France
CH Emile Roux
Le Puy-en-Velay, France
Hôpital Edouard Herriot
Lyon, France
APHP - Hôpital Cochin
Paris, France
CH Roanne
Roanne, France
CHU Saint-Etienne
Saint-Etienne, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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