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NOAC9 - Circulating Tumor DNA Guided Follow-Up in Anal Cancer

RecruitingNAAges 18 Years - anyAllAarhus University Hospital
NCT05572801 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study investigates if circulating tumor DNA can improve the detection of early treatment failure or recurrence in localized squamous cell carcinoma of the anus (SCCA) after curative chemoradiotherapy thereby increasing the potential for cure. This will be done by comparing the standard follow-up program with ctDNA guided imaging follow-up. Secondly, the aim is to establish early interventions against late morbidities.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with SCCA eligible for definitive (chemo)radiotherapy * ≥ 18 of years * Written and oral consent Exclusion Criteria: * Conditions that will contraindicate blood samples * Conditions that will contraindicate a PET-CT scan. * Potential lack of compliance to standard FU program and study participation.
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What it tests

  • AMR B: HPV positive ctDNA guided imaging in follow-up
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Where

13 sites
Department of Oncology Herlev and Gentofte Hospital
Herlev, Denmark
Department of Oncology, Vejle Hospital
Vejle, Denmark
Aarhus University Hospital
Aarhus, Denmark
Tampere University Hospital
Tampere, Finland
Turku University Hospital
Turku, Finland
Haukeland University Hospital
Bergen, Norway
Oslo University Hospital
Oslo, Norway
University Hospital of North Norway
Tromsø, Norway

…and 5 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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