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Expanding Medication-Assisted Therapies in Central Asia

RecruitingNAAges 18 Years - anyAllYale University
NCT05579470 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more effective when combined with antiretroviral therapy (ART). The investigators propose to use the Network for the Improvement of Addiction Treatment (NIATx) implementation strategy to scale-up OAT in three diverse Central Asian countries (Kazakhstan, Kyrgyzstan, Tajikistan) and guided by the Exploration-Planning-Implementation-Sustainment (EPIS) framework. Understanding the trajectories of implementation and scale-up in this context may emerge through creating communities of practice, especially when cohesion and competence evolves, and may guide other healthcare delivery challenges in the region (e

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📋 Eligibility rules (as published)
Inclusion Criteria: i. Aim 1: The inclusion criteria for Aim 1 Consists of: 1. Quantitative surveys for PWID 1. 18 years or older 2. Meeting DSM-V criteria for opioid dependence 3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days 2. Organizational Assessments for OAT Delivery Staff 1. 18 years or older 2. Currently working as an OAT delivery professional at an OAT delivery site 3. Focus Groups (PWID on OAT) 1. 18 years or older 2. Meeting DSM-V criteria for opioid dependence 3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days 4. Focus Groups (PWID not on OAT) 1. 18 years or older 2. Meeting Diagnostic and Statistical Manual of Mental Disorders(DSM)-V criteria for opioid dependence 3. Be OAT naïve (defined as never having been on OAT or having not received treatment for \> 1 year) 5. Focus Groups (OAT delivery staff) 1. 18 years or older 2. Currently working as an OAT delivery professional at an OAT delivery site ii. Aim 2: The inclusion criteria for Aim 2 consists of: 1. 18 years or older 2. Currently assigned as a Chief Narcologist for an Oblast iii. Aim 3: The inclusion criteria for Aim 3 consists of: 1. 18 years or older 2. Authorized as a professional to work at an OAT delivery site Exclusion Criteria: * Not willing to provide consent
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What it tests

  • NIATx
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Where

4 sites
Yale University
New Haven, United States
Columbia University Global Health Research Center of Central Asia
Almaty, Kazakhstan
Den Sooluk Nuru
Bishkek, Kyrgyzstan
Institute for International Health and Education
Dushanbe, Tajikistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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