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IVIG vs SCIG in CIDP

RecruitingPhase 1Ages 18 Years - 65 YearsAllRutgers, The State University of New Jersey
NCT05584631 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Current dosing practices for immunoglobulin G (IgG) may be inadequate in extreme body weight. The current study will evaluate the influence of body composition on intravenous and subcutaneous administration of immunoglobulin G in patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged \>18 years with a current diagnosis of CIDP (based on European Federation of Neurological sciences / Peripheral Nerve Society CIDP diagnostic criteria). * 1:1 conversion of IVIG to SCIG (weekly dose conversion) must fall within 0.2-to-0.4 mg/kg dose for SCIG. Exclusion Criteria: * Patients receiving IVIG for indications other than CIDP will be excluded. * Patients with liver impairment (elevations in liver enzymes of greater than 3 times the upper limit of normal) or reduced renal function (CrCl \< 50 mL/min) will be excluded * Active malignancies * Diabetes * Myasthenia gravis * Immunodeficiency * Autoimmune disease
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What it tests

  • Intravenous immune globulin G
  • Subcutaneous immune globulin G
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Where

1 site
Rutgers, The State University of New Jersey Clinical Research Center
New Brunswick, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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