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Iodine Uptake After a Low Iodine Diet

RecruitingNAAges 18 Years - 75 YearsAllUniversity Medical Center Groningen
NCT05599139 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days. The main question it aims to answer is: • What is the difference in iodine uptake before and after a LID of 7 days? Uptake of a low dose of 123-iodine will be measured in participants before and after a low iodine diet of 7 days. Researchers will compare the uptake (%) before and after the LID.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients, men and women above the age of 18 years, have to be diagnosed with DTC and have to follow a LID prior to the 131I ablation therapy according to the Dutch DTC guideline * Patients have to be fit to adhere to the study protocol * Patients have to be able to read and understand the Dutch language Exclusion Criteria: * Age \< 18 years * Patients using amiodarone * Patients receiving iodinated contrast \< 3 months before the LID * Pregnancy * Patients prepared for ablation therapy with rhTSH * Renal impairment, EGFR \<30ml/min/1,73m2
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What it tests

  • Low iodine diet
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Where

1 site
UMCG
Groningen, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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