Multi Center Observation of Sentinel Skin Graft for Detecting Acute Rejection After Renal Transplantation

Inclusion Criteria: 1. Patients with end-stage renal disease undergoing renal transplantation; 2. 18-60 years old; 3. Postoperative follow-up points are complete (visit the hospital every week in the first month after surgery, every two weeks in 2-3 months, every four to six months, and every three months in 7-12 months. Follow up at any time when skin rejection is observed. The follow-up time may be adjusted when the condition changes); 4. The participants had good compliance, volunteered to participate in the test and signed the informed consent form. Exclusion Criteria: 1. Untreated or disseminated malignant tumor; 2. Active period of infectious diseases; 3. Serious cardiovascular disease occurred recently; 4. Combined with other important organ failure; 5. History of mental illness or cognitive impairment;